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HRID1272457

反应详情

EQUATION

反应方程式

HRID 1272457 的结构方程式

REACTANTS

反应物

2
结构：O=C(O)COc1ccc(O)cc1
HCID15881

Acetic acid, (4-hydroxyphenoxy)-

C8H8O4

结构：Nc1ccccc1-c1cc2ccccc2[nH]1
HCID735966

2-(2-Aminophenyl)indole

C14H12N2

PRODUCTS

生成物

1
结构：O=C(COc1ccc(O)cc1)Nc1ccccc1-c1cc2ccccc2[nH]1
HCID18455693

未命名化合物

收率 30%

PROCEDURE

实验过程

Prepared from 2-(2-aminophenyl) indole and (4-hydroxyphenoxy) acetic acid in 30% yield following procedure 1. The product was crystallized from methanol. 89% Purity by LC/MS (230 DAD), Mass-spec [M+H+]=359, 1H NMR (MeOH-d4): 4.52 s (2H), 6.55 d, 9 Hz (2H), 6.58 s (1H), 6.61 d, 9 Hz (2H), 7.09 t, 8 Hz (1H), 7.18 t, 8 Hz (1H), 7.26 t, 8 Hz (1H), 7.37–7.43 m (2H), 7.56 t, 8 Hz (2H), 8.38 d, 8 Hz (1H).

WORKUP

后处理

  1. customThe product was crystallized from methanol
  2. custom9 Hz (2H), 6.58 s (1H), 6.61 d, 9 Hz (2H), 7.09 t, 8 Hz (1H), 7.18 t, 8 Hz (1H), 7.26 t, 8 Hz (1H), 7.37–7.43 m (2H), 7.56 t, 8 Hz (2H), 8.38 d, 8 Hz (1H)