HRID127575

反应详情

EQUATION

反应方程式

REACTANTS

反应物

$结构：CCCCC[C@@H](/C=C/[C@@H]1[C@@H](C/C=C\CCCCOC(=O)NC)[C@@H](O[Si](Cc2ccccc2)(Cc2ccccc2)Cc2ccccc2)C[C@H]1OC1CCCCO1)OC1CCCCO1$

HCID70566973

未命名化合物

PRODUCTS

生成物

$结构：CCCCC[C@H](O)/C=C/[C@@H]1[C@@H](C/C=C\CCCCOC(=O)NC)[C@@H](O)C[C@H]1O$

HCID70567932

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID21877175

未命名化合物

PROCEDURE

实验过程

At 50°, 250 mg. of (5Z,13E)-(8R,9S,11R,12R,15S)-1-(N-methylcarbamoyloxy)-11,15-bis(tetrahydropyran-2-yloxy)-9-tribenzylsilyloxy-5,13-prostadiene was stirred for 5 hours in 15 ml. of a mixture of glacial acetic acid/water/tetrahydrofuran (65/35/10). The mixture was evaporated under vacuum and the residue purified by chromatography on silica gel with ether/dioxane (7+3), thus obtaining 105 mg. of the title compound as a colorless oil.

WORKUP

后处理

customAt 50°
customThe mixture was evaporated under vacuum
customthe residue purified by chromatography on silica gel with ether/dioxane (7+3)
customthus obtaining 105 mg