HRID127576

反应详情

EQUATION

反应方程式

REACTANTS

反应物

$结构：CCCCC[C@@H](/C=C/[C@H]1[C@H](OC2CCCCO2)CC(=O)[C@@H]1C/C=C\CCCCOC(=O)NC)OC1CCCCO1$

HCID70567581

未命名化合物

PRODUCTS

生成物

$结构：CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1C/C=C\CCCCOC(=O)NC$

HCID70566919

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID21877175

未命名化合物

PROCEDURE

实验过程

At 40°, 300 mg. of (5Z,13E)-(8R,11R,12R,15S)-1-(N-methylcarbamoyloxy)-11,15-bis(tetrahydropyran-2-yloxy)-5,13-prostadien-9-one was agitated with 9 ml. of a mixture of glacial acetic acid/water/tetrahydrofuran (65/35/10) for 6 hours. The mixture was then evaporated to dryness under vacuum. After purifying the residue by chromatography on silica gel (ether/ethyl acetate 7+3), 145 mg. of the title compound was obtained as a colorless oil.

WORKUP

后处理

customAt 40°
customThe mixture was then evaporated to dryness under vacuum
customAfter purifying the residue by chromatography on silica gel (ether/ethyl acetate 7+3), 145 mg