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HRID1295724

反应详情

EQUATION

反应方程式

HRID 1295724 的结构方程式

REACTANTS

反应物

3
结构：BrCc1ccccc1
HCID7498

alpha-Bromotoluene

C7H7Br

结构：O=c1c(N2CCNCC2)nccn1CCOc1cc(F)c(F)cc1F
HCID10405848

2(1H)-Pyrazinone, 3-(1-piperazinyl)-1-[2-(2,4,5-trifluorophenoxy)ethyl]-

C16H17F3N4O2

结构：Cl.O=c1c(N2CCNCC2)nccn1CCOc1cc(F)c(F)cc1F
HCID11639709

未命名化合物

PRODUCTS

生成物

1
结构：Cl.O=c1c(N2CCN(Cc3ccccc3)CC2)nccn1CCOc1cc(F)c(F)cc1F
HCID10435302

未命名化合物

PROCEDURE

实验过程

The title compound was prepared according to the procedure of Example 60 starting from 3-(1-piperazinyl)-1-[2-(2,4,5-trifluorophenoxy)ethyl]-2(1H)-pyrazinone (0.35 g, 1.0 mmol; from the free base of Example 3) and benzyl bromide (0.19 g, 1.1 mmol) Yield: 0.17 g (35%); HPLC purity: 99%; mp 214-214.5° C. HRMS calc for C23H23F3N4O2 (M)+ 444.1773, found 444.1789.