反应详情

24 mg of 1-(2-(6-(4-oxazol-5-yl-phenoxy)-2-pyridin-2-yl-3-(2-trimethylsilanyl-ethoxymethyl)-3H-benzimidazol-5-yl)-pyrrolidin-1-yl)-ethanone was dissolved in 1 ml of trifluoroacetic acid, and the reaction liquid was stirred at room temperature for 2 hours. The solvent was evaporated away under reduced pressure, and the resulting residue was purified through reversed-phase middle-pressure liquid chromatography (ODS-AS-360-CC (by YMC), mobile phase: water-acetonitrile-0.1% trifluoroacetic acid) to obtain the entitled compound as a yellow oily substance.

1. customthe reaction liquid
2. customThe solvent was evaporated away under reduced pressure
3. customthe resulting residue was purified through reversed-phase middle-pressure liquid chromatography (ODS-AS-360-CC (by YMC), mobile phase: water-acetonitrile-0.1% trifluoroacetic acid)
4. customto obtain the entitled compound as a yellow oily substance