反应详情

The title compound was prepared from (2S)-3-[4-(1-tert-butoxycarbonyl-1-methyl-ethoxy)-phenyl]-2-methoxy-propionic acid ethyl ester (PREPARATION 5, step 1) via the same procedure used to prepare (2S)-3-(4-carboxymethoxy-phenyl)-2-methoxy-propionic acid ethyl ester (example 121, step 2) to produce a yellow oil. 1H-NMR (CDCl3, 200.15 MHz): 7.10 (d, 2H, J=8.3), 6.77 (d, 2H, J=8.3), 4.14 (c, 2H, J=6.9), 3.89 (t, 1H, J=6.5), 3.34 (s, 3H), 2.94 (d, 2H, J=6.5), 1.55 (s, 6H), 1.19 (t, 3H, J=6.9).

1. customto produce a yellow oil