反应详情

The title compound was prepared following general procedures described above from 4-(4-Chlorophenyl)-1-(4-hydroxy-pyrrolidin-3-yl)-piperidin-4-ol and 4,7-dichloroquinazoline. 1H-NMR (300 MHz, DMSO): δ1.57 (2 H, m), 1.90 (2 H, m), 2.60-2.70 (3 H, m), 2.96 (2 H, m), 3.70 (1 H, m), 3.85 (1 H, m), 4.10 (2 H, m), 4.36 (1 H, m), 4.90 (1 H, s), 5.32 (1 H, d), 7.40 (4 H, dd), 7.48 (1 H, m), 7.73 (1 H, d), 8.30 (1 H, d), 8.45 (1 H, s). Retention Time (LC, method, AA standard): 1.48 min. MS (M+H+): 459.

1. custom1.48 min