反应详情

{4-[(2R,3R)-3-[2-(2,3-Dihydro-benzofuran-6-yl)-2-oxo-ethylsulfanyl]1-(4-fluoro-phenyl)-4-oxo-azetidin-2-yl]-phenoxy}-acetic acid tert-butyl ester (77 mg, 0.137 mmol) was dissolved in formic acid (3 mL) and the solution was stirred for 1 h at room temperature. The solvent was removed under reduced pressure and the residue was dissolved in DCM. The solution was washed with water and then concentrated under reduced pressure. The residue was freeze-dried from MeCN/water to give the title compound.

1. customThe solvent was removed under reduced pressure
2. dissolutionthe residue was dissolved in DCM
3. washThe solution was washed with water
4. concentrationconcentrated under reduced pressure
5. dry with materialThe residue was freeze-dried from MeCN/water