反应详情

The procedure of Example 1 is repeated using 1.95 g (12.5 mmol) of 1-oxyl-2,2,6,6-tetramethylpiperidine, 3.92 g (38 mmol) of tert-butyl nitrite, 12.5 mg (0.125 mmol) of copper(II) fluoride, 120 mL of pyridine and 4.93 g (25 mmol) of 4-aminobenzophenone in 40 mL of pyridine at 70° C. The crude product obtained is purified by vacuum flash chromatography (heptane) to give 3.40 g of the title compound as a light yellow oil in 80.6% yield. The structure is confirmed by 1Hnmr, elemental and mass spectrographic analysis.

1. customat 70° C
2. customThe crude product obtained
3. customis purified by vacuum flash chromatography (heptane)