反应详情

1.0 ml of phenyl chloroformate is added, in small portions, to a solution, cooled to 0° C., of 1.3 g of 4-chloro-3-(2-nitro-3-chlorophenyl)pyrazole in 20 ml of pyridine. Stirring is continued for 8 hours at room temperature. The reaction mixture is concentrated dryness under reduced pressure and taken up in 100 ml of an H2O/ethyl acetate (1/1) mixture. The organic phase is dried over MgSO4 and concentrated under reduced pressure. The residual solid is purified by recrystallisation from diisopropyl ether.

1. concentrationThe reaction mixture is concentrated dryness under reduced pressure
2. dry with materialThe organic phase is dried over MgSO4
3. concentrationconcentrated under reduced pressure
4. customThe residual solid is purified by recrystallisation from diisopropyl ether