HRID1388276

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID383824

O-Methyl-N,N'-diisopropylisourea

C8H18N2O

$结构：CC1(C)[C@H](/C=C2\CCSC2=O)[C@H]1C(=O)O$

HCID22826578

未命名化合物

PRODUCTS

生成物

$结构：COC(=O)[C@@H]1[C@@H](/C=C2\CCSC2=O)C1(C)C$

HCID86739247

未命名化合物

收率 18.8%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

Using the procedure of Example 17, 4 g of (1R,trans) 2,2-dimethyl-3-[(E) (dihydro-2-oxo-3-(2H)-thienylidene)-methyl]-cyclopropane-carboxylic acid and 3.5 g of methyl N,N'-diisopropylcarbamimidate were reacted to obtain 0.8 g of methyl (1R,trans) 2,2-dimethyl-3-[(E) (dihydro-2-oxo-3-(2H)-thienylidene)-methyl]-cyclopropane-1-carboxylate with a specific rotation of [α]D20 =+63.5°±1.5° (c=1.1% in ethanol).

WORKUP

后处理

customwere reacted