反应详情

This compound was synthesized from 2-(2-(4-chlorophenyl)thiazol-4-yl)acetonitrile and 2-chloro-N-(2-chloroethyl)-N-methylethanamine hydrochloride as described in example 16 step 1b (350 mg, yield 32%). 1H NMR (300 MHz, CDCl3) δ 7.91-7.88 (d, J=8.6 Hz, 2H), 7.43-7.40 (d, J=8.6 Hz, 2H), 7.32 (s, 1H), 3.03-2.98 (m, 2H), 2.57-2.38 (m, 7H), 2.26-2.21 (m, 2H). MS (ESI) m/z: Calculated for C16H16ClN3S: 317.08. found: 318.2 (M+H)+.