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HRID1401014

反应详情

EQUATION

反应方程式

HRID 1401014 的结构方程式

REACTANTS

反应物

2
结构：C=C(C)[C@@H]1CC[C@]2(NCCN3CCS(=O)(=O)CC3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(OS(=O)(=O)C(F)(F)F)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12
HCID71698666

未命名化合物

结构：CC1(C)OB(C2=CCC3(CCOC3=O)CC2)OC1(C)C
HCID86692369

未命名化合物

PRODUCTS

生成物

1
结构：C=C(C)[C@@H]1CC[C@]2(NCCN3CCS(=O)(=O)CC3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(C6=CCC7(CCOC7=O)CC6)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12
HCID86692368

未命名化合物

PROCEDURE

实验过程

The title compound was prepared following the procedure described in general procedure Step 5, using (1R,3aS,5aR,5bR,7aR,11aR,11bR,13aR,13bR)-3a-((2-(1,1-dioxidothiomorpholino)ethyl)amino)-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)-2,3,3a,4,5,5a,5b,6,7,7a,8,11,11a,11b,12,13,13a,13b-octadecahydro-1H-cyclopenta[a]chrysen-9-yl trifluoromethanesulfonate and 8-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-oxaspiro[4.5]dec-7-en-1-one as reactants and 85° C. The product was obtained as a mixture of diasteroisomers and was used without further purification in the next step. MS: m/e 721 (M+H)+, 2.72 min (method 4).

WORKUP

后处理

  1. custom85° C
  2. customThe product was obtained as a mixture of diasteroisomers
  3. customwas used without further purification in the next step
  4. customm/e 721 (M+H)+, 2.72 min (method 4)