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HRID1401039

反应详情

EQUATION

反应方程式

HRID 1401039 的结构方程式

REACTANTS

反应物

2
结构：COC(=O)C1(NC(C)=O)CCC(=O)CC1
HCID10584690

未命名化合物

结构：C=C(C)[C@@H]1CC[C@]2(NCCN3CCS(=O)(=O)CC3)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC=C(OS(=O)(=O)C(F)(F)F)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12
HCID71698666

未命名化合物

PRODUCTS

生成物

2
结构：COC(=O)C1(NC(C)=O)CC=C(OS(=O)(=O)C(F)(F)F)CC1
HCID86692399

未命名化合物

结构：CC(=O)NC1(C(=O)[O-])CCC(=O)CC1
HCID86692400

未命名化合物

PROCEDURE

实验过程

The title compound was prepared following the procedure described on step 6 of method 2 for the preparation of intermediate 1, using methyl 1-acetamido-4-oxocyclohexanecarboxylate, as the reactant. 1-acetamido-4-oxocyclohexanecarboxylate was prepared following the procedures described in Journal of Chem. Soc., Perkin Trans. I, 1999, pp. 3375-3379. (84.0% yield), MS: m/e 346.1 (M+H)+, 2.213 min (method ?). 1H NMR (400 MHz, CHLOROFORM-d) δ 6.24 (s, 1H), 5.69 (td, J=3.3, 1.4 Hz, 1H), 3.82-3.58 (m, 3H), 2.87-2.67 (m, 1H), 2.61-2.44 (m, 2H), 2.42-2.33 (m, 2H), 2.19-2.07 (m, 1H), 2.01-1.94 (m, 3H). 19F NMR (376 MHz, CHLOROFORM-d) δ −74.02 (s, 3F).

WORKUP

后处理

  1. customm/e 346.1 (M+H)+, 2.213 min (method ?)