反应详情

The title compound was prepared following the method described in step 2 for the preparation of methyl 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)spiro[3.3]hept-5-ene-2-carboxylate, using methyl 1-acetamido-4-(((trifluoromethyl)sulfonyl)oxy)cyclohex-3-enecarboxylate as the reactant. (48.4% yield). MS: m/e 325.25 (M+H)+, 2.126 min (method 8). 1H NMR (400 MHz, CHLOROFORM-d) δ 6.42 (br. s., 1H), 5.90 (s, 1H), 3.83-3.59 (m, 3H), 2.65 (d, J=18.8 Hz, 1H), 2.35 (d, J=18.1 Hz, 1H), 2.25 (d, J=11.0 Hz, 2H), 2.13-2.03 (m, 1H), 1.98-1.90 (m, 3H), 1.88-1.75 (m, 1H), 1.36-1.18 (m, 12H).

1. customm/e 325.25 (M+H)+, 2.126 min (method 8)