反应详情

4.3 g (20 mmol) of 4-acetyloxy-2,2,6,6-tetramethylpiperidine-N-oxide synthesized by the method described in Synthesis Example 1 was dissolved in 20 mL of cumene and 11.7 g (80 mmol) of t-butyl peroxide was added slowly. After a nitrogen bubbling for 30 minutes, it was transferred to a UV laboratory reaction apparatus (System1) made by Heraeus K. K. Light irradiation was performed using a TQ150 type lamp for 10 minutes to carry out a reaction. The reaction mixture was concentrated by a rotary evaporator, and the residue was purified by column chromatography (silica gel, hexane/ethyl acetate=5/1, volume ratio) to obtain 5.5 g of 1-cumyloxy-2,2,6,6-tetramethyl-4-acetyloxypiperidine was obtained (82.3% of yield).

1. customdescribed in Synthesis Example 1
2. customit was transferred to a UV laboratory reaction apparatus (System1)
3. customLight irradiation
4. customfor 10 minutes
5. customa reaction
6. concentrationThe reaction mixture was concentrated by a rotary evaporator
7. customthe residue was purified by column chromatography (silica gel, hexane/ethyl acetate=5/1, volume ratio)