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HRID1428970

反应详情

EQUATION

反应方程式

HRID 1428970 的结构方程式

REACTANTS

反应物

3
结构：COC(=O)c1cccc(B(O)O)c1
HCID2734714

3-Methoxycarbonylphenylboronic acid

C8H9BO4

结构：CNC(=O)c1cccc(-c2ccc(O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]3O)c(C)c2)c1
HCID57413864

未命名化合物

结构：CC(=O)OC[C@H]1O[C@H](Oc2ccc(Br)cc2C)[C@@H](CC(=O)[O-])[C@H](OC(C)=O)[C@H]1OC(C)=O
HCID86674309

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)c1cccc(-c2ccc(O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]3O)c(C)c2)c1
HCID57413728

未命名化合物

收率 54%

PROCEDURE

实验过程

4c was prepared using the same procedure as for 5b with [(2R,3S,4S,5R,6R)-4,5-diacetoxy-6-(acetoxymethyl)-2-(4-bromo-2-methyl-phenoxy)tetrahydropyran-3-yl]acetate and 3-methoxycarbonylphenyl boronic acid as the reactants. Yield: 54%. 1H NMR (300 MHz, METHANOL-d4) δ ppm 8.20 (t, J=1.51 Hz, 1H), 7.94 (td, J=1.41, 7.90 Hz, 1H), 7.77-7.87 (m, 1H), 7.52 (t, J=7.55 Hz, 1H), 7.39-7.48 (m, 2H), 7.27-7.38 (m, 1H), 5.56 (d, J=1.65 Hz, 1H), 4.08 (dd, J=1.92, 3.30 Hz, 1H), 3.94-4.01 (m, 1H), 3.90-3.94 (m, 3H), 3.68-3.83 (m, 3H), 3.55-3.65 (m, 1H), 2.31 (s, 3H). MS (ESI): found [M+Na]+, 427.1