4-BENZAMIDOPHENYLBORONIC ACID → HCID 66779935, Verbindung

HRID 1470380Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1470380
Cl[C:2]1[CH:7]=[CH:6][N:5]=[C:4]2[CH:8]=[C:9]([C:11]3[CH:16]=[C:15]([O:17][CH3:18])[C:14]([O:19][CH3:20])=[C:13]([O:21][CH3:22])[CH:12]=3)[O:10][C:3]=12.[C:23]([NH:31][C:32]1[CH:37]=[CH:36][C:35](B(O)O)=[CH:34][CH:33]=1)(=[O:30])[C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1>>[CH3:22][O:21][C:13]1[CH:12]=[C:11]([C:9]2[O:10][C:3]3[C:4](=[N:5][CH:6]=[CH:7][C:2]=3[C:35]3[CH:34]=[CH:33][C:32]([NH:31][C:23](=[O:30])[C:24]4[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=4)=[CH:37][CH:36]=3)[CH:8]=2)[CH:16]=[C:15]([O:17][CH3:18])[C:14]=1[O:19][CH3:20]

Komponenten

3

Edukt 2

HCID 118067724-BENZAMIDOPHENYLBORONIC ACIDHCID 667789647-Chloro-2-(3,4,5-trimethoxyphenyl)furo[3,2-b]pyridine

Produkt 1

HCID 66779935HCID 66779935, Verbindung

Versuchsvorschrift

The title compound was prepared by procedure C using 7-chloro-2-(3,4,5-trimethoxyphenyl)furo[3,2-b]pyridine (45.00 mg; 0.14 mmol; 1.00 eq.) instead of 7-chloro-2-iodo-furo[3,2-b]pyridine, and 4-benzamidophenylboronic acid (37.32 mg; 0.15 mmol; 1.10 eq.) instead of 4-fluorophenylboronic acid and was obtained as a pale yellow solid (55 mg, 81%). (HPLC (method F): 94%, RT: 4.14 min); MS (m/z) 481 [M+H]+, RT: 4.1 min.

Quellen und Nachweise

ORD-Eintrag
ord-1390c6eb4d46474cac42925430b773a1
Quelldatensatz
uspto-grants-2015_04
Patentnummer
US09006440B2

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