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HRID1486705

反应详情

EQUATION

反应方程式

HRID 1486705 的结构方程式

REACTANTS

反应物

3
结构：COc1ccc([N+](=O)[O-])cc1C=O
HCID90685

Benzaldehyde, 2-methoxy-5-nitro-

C8H7NO4

结构：CC(C)(C)NC(=O)C1CCNCC1
HCID7175833

未命名化合物

结构：COc1ccc([N+](=O)[O-])cc1CN1CCC(C(=O)NC(C)(C)C)CC1
HCID86706538

未命名化合物

PRODUCTS

生成物

1
结构：COc1ccc(N)cc1CN1CCC(C(=O)NC(C)(C)C)CC1
HCID86706537

未命名化合物

PROCEDURE

实验过程

The title compound is prepared according to the reactions described for BB-5 above starting from 2-methoxy-5-nitro-benzaldehyde and piperidine-4-carboxylic acid tert-butylamide yielding after reductive amination 1-(2-methoxy-5-nitro-benzyl)-piperidine-4-carboxylic acid tert-butylamide; LC-MS A: tR=0.61 min; [M+H]+=350.18 followed by reduction with stannous chloride the title compound; LC-MS A: tR=0.42 min; [M+H]+=320.24.

WORKUP

后处理

  1. customThe title compound is prepared