反应详情

This compound was prepared from 2-(tert-butyl)dimethylsilyloxybenzaldehyde (7) (4.23 g, 17.9 mmol) in the manner previously described for the synthesis of benzyl alcohol 5, affording 2.81 g (66%) of the silyloxybenzyl alcohol as a pale yellow oil. 1H NMR (400 MHz, CDCl3) δ0.26 [s, 6H, Si(CH3)2 ], 1.02 [s, 9H, SiC(CH3)3 ], 4.68 (d, 2H, J=6.3 Hz, CH2OH), 6.81 (d, 1H, J=6.3 Hz, Ar--H), 6.95 (dd, 1H, J=7.1, 7.1 Hz, Ar--H), 7.17 (ddd, 1H, J=9.5, 7.8 1.7 Hz, Ar--H), 7.30 ppm (dd, 1H, J=5.8, 1.6 Hz, Ar--H).