反应详情

This compound was prepared from 2-(tert-butyl)dimethylsilyloxybenzyl alcohol (8) (2.81 g, 11.8 mmol) in the manner previously described for the synthesis of benzyl bromide 6, affording 1.14 g (32%) of the silyloxybenzyl bromide as a colorless oil. 1H NMR (400 MHz, CDCl3) δ0.30 [s, 6H, Si(CH3)2 ], 1.07 [s, 9H, SiC(CH3)3 ], 4.54 (s, 2H, CH2Br), 6.83 (d, 1H, J=6.2 Hz, Ar--H), 6.93 (dd, 1H, J=7.1, 7.1 Hz, Ar--H), 7.19 (ddd, 1H, J=9.4, 7.9, 1.6 Hz, Ar--H) 7.34 ppm (dd, 1H, J=5.8, 1.6 Hz, Ar--H). ##STR4##