反应详情

This compound was prepared from 5,5-dimethylcyclohex-2-en-1-one (11) (0.600 g, 4.83 mmol) and p-nitrobenzyl bromide (1.581 g, 7.32 mmol) in the manner previously described for the synthesis of enone 13, affording 627 mg (50%), of the nitro-enone as a pale yellow oil. 1H NMR (400MHz, CDCl3) δ1.02 and 1.18 (2s, 2×3H, geminal-CH3 's), 2.83 and 3.10 (d of ABq, 2H, benzylic-CH2), 6.00 (ddd, 1H, 2-H), 6.81 (ddd, 1H, 3-H), 7.38 and 8.10 ppm (ABq, 2×2H, Ar--H).

1. customaffording 627 mg (50%)