反应详情
EQUATION
反应方程式
REACTANTS
反应物
Benzaldehyde
C7H6O
Propanal
C3H6O
Tetraethylthiuram disulfide
C10H20N2S4
Thymidine
C10H14N2O5
Adenosine 5′-(trihydrogen diphosphate), 2′-(dihydrogen phosphate), P′→5′-ester with 3-(aminocarbonyl)-1-β-D-ribofuranosylpyridinium
C21H29N7O17P3+
Acrolein
C3H4O
(4-(2-Hydroxyethyl)-1-piperazineethanesulfonic acid
C8H18N2O4S
Adenosine 5'-(trihydrogen diphosphate), P'→5'-ester with 1,4-dihydro-1-.beta.-D-ribofuranosyl-3-pyridinecarboxamide
C21H29N7O14P2
PRODUCTS
生成物
PROCEDURE
实验过程
Materials: SDA was prepared by acid hydrolysis of the corresponding bioacetal supplied by the Department of Pharmaceutical Development at our Institute. [3H]-Thymidine was purchased from New England Nuclear, Boston, Mass. Concanavalin A, horse serum, RPMI-1640 and HEPES were from Gibco, Grand Island, N.Y. NAD and NADP were purchased from Boehringer, Mannheim. Acrolein and disulfiram were obtained from Aldrich Chemical Co., Milwaukee, Wis. Propionaldehyde and benzaldehyde were from Eastman Kodak Chemical Co., Rochester, N.Y. Diethyl aminobenzaldehyde (DEAB) was kindly provided by Dr. John Hilton, Johns Hopkins School of Medicine, Baltimore, Md.
WORKUP
后处理
- customMaterials: SDA was prepared by acid hydrolysis of the corresponding bioacetal