反应详情

Using the procedure of Example 6, 1.26 g of the lactone of (1R,cis) 2,2-dimethyl-3-dihydroxymethyl-cyclopropane-carboxylic acid and 3.13 g of the product of Step A were reacted to obtain after crystallization from hexane 0.89 g of (1R,cis,ΔZ) 2,2-dimethyl-3-[3-oxo-3-propoxy-1-propenyl]-cyclopropane-carboxylic acid melting at 59° C. and having a specific rotation of [α]D20 =+77°±1.5° (c=1% in chloroform).

1. customwere reacted
2. customto obtain
3. customafter crystallization from hexane 0.89 g of (1R,cis,ΔZ) 2,2-dimethyl-3-[3-oxo-3-propoxy-1-propenyl]-cyclopropane-carboxylic acid melting at 59° C.
4. customa specific rotation of [α]D20 =+77°±1.5° (c=1% in chloroform)