反应详情

Following the procedure as described in Example 3, STEP B, the title compound was prepared from 2-nitro-4-(2-trifluoromethyl-pyridin-4-yl)-phenylamine (84.5 mg, 0.298 mmol, as prepared in the previous step) and (E)-3-(tetrahydro-pyran-4-yl)-acrylic acid (prepared as described in PCT Publication WO 2005/101989 (A2, A3), 60.5 mg, 0.388 mmol) and was obtained as a yellow solid.

1. customwas obtained as a yellow solid