反应详情

This compound is essentially prepared as described in Example 36 by using 2-chloro-4,4-difluoro-1′-[(3-methyl-1H-pyrazol-4-yl)methyl]spiro[5H-thieno[2,3-c]pyran-7,4′-piperidine] and 3-(2-bromo-pyrid-3-yl)isoxazole as starting material. Residue is purified by normal phase Isco chromatography (ethyl acetate is used as eluent) to yield 45% of the title compound: mass spectrum (m/z): 518 (M+1)

1. customThis compound is essentially prepared
2. customResidue is purified by normal phase Isco chromatography (ethyl acetate is used as eluent)