HRID1518355
反应详情
EQUATION
反应方程式
REACTANTS
反应物
PRODUCTS
生成物
AUXILIARIES
试剂、催化剂与溶剂
PROCEDURE
实验过程
A mixture of compound 41A (90 mg, 0.102 mmol), 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (29.7 mg, 0.153 mmol), Na2CO3 (108 μl, 0.102 mmol) (1M) and (Ph3P)2Cl2Pd (7.15 mg, 10.19 μmol) in EtOH-DME-H2O (7:3:2, 4 ml) was in a Smith microwave synthesizer at 120° C. for 30 min and then concentrated. The residue was purified by flash chromatography to give the compound 73A. LCMS (APCI) m/e 824 (M+H).
WORKUP
后处理
- concentrationconcentrated
- customThe residue was purified by flash chromatography