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HRID1527370

反应详情

EQUATION

反应方程式

HRID 1527370 的结构方程式

REACTANTS

反应物

2
结构：CCOC(C)=O
HCID8857

Ethyl acetate

C4H8O2

结构：CC(C)(C)OC(=O)N1C[C@](C)(F)C[C@H]1C(=O)N[C@H](CO)c1cccc(Cl)c1F
HCID68283867

未命名化合物

PRODUCTS

生成物

1
结构：COC[C@@H](NC(=O)[C@@H]1C[C@@](C)(F)CN1C(=O)OC(C)(C)C)c1cccc(Cl)c1F
HCID68284566

未命名化合物

PROCEDURE

实验过程

was prepared according to Scheme B9 (Step B) from (2S,4R)-2-[(S)-1-(3-chloro-2-fluoro-phenyl)-2-hydroxy-ethylcarbamoyl]-4-fluoro-4-methyl-pyrrolidine-1-carboxylic acid tert-butyl ester. TLC, Rf (EtOAc)=0.90; MS (UPLC-MS): 433.4/435.4 [M+H]+, 477.4 [M+HCOO]−; tR (HPLC conditions a): 3.73 min.

WORKUP

后处理

  1. customwas prepared
  2. custom3.73 min.