HRID15555
反应详情
EQUATION
反应方程式
REACTANTS
反应物
PRODUCTS
生成物
PROCEDURE
实验过程
{5-[[2-(4-Chloro-phenoxy)-ethyl]-(4-fluoro-benzenesulfonyl)-amino]-2-propyl-benzoimidazol-1-yl}-acetic acid tert-butyl ester was treated with TFA (2 mL) for 2 hours, concentrated, and purified by preparative LCMS to give the title compound. 1H NMR (d6-DMSO) δ7.71 (m, 2H), 7.41 (m, 2H), 7.28 (m, 3H), 7.11 (d, 1H), 6.95 (d, 1H), 6.82 (m, 2H), 4.66 (s, 2H), 3.98 (m, 4H), 2.71 (t, 2H), 1.72 (m, 2H), 0.99 (t, 3H). MS calculated for C26H25FClN3O5S—H: 544, observed: 544.
WORKUP
后处理
- concentrationconcentrated
- custompurified by preparative LCMS