反应详情

[5 -(Benzyl-cyclopentanecarbonyl-amino)-2-propyl-benzoimidazol-1-yl]-acetic acid tert-butyl ester (0.12 mmol) was treated with TFA (2 mL) for 2 hours, concentrated, and purified by preparative LCMS to give the title compound. 1H NMR (d6-DMSO) δ7.47 (d, 1H), 7.21 (m, 6H), 6.95 (m, 1H), 5.08 (s, 2H), 4.87 (s, 2H), 2.73 (t, 2H), 1.71 (m, 9H), 1.33 (m, 2H), 0.99 (t, 3H). MS calculated for C25H29N3O3+H: 420, observed: 420.

1. concentrationconcentrated
2. custompurified by preparative LCMS