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HRID1614873

反应详情

EQUATION

反应方程式

HRID 1614873 的结构方程式

REACTANTS

反应物

2
结构：COc1cc([C@@H](C)N)ccc1F.Cl
HCID53484667

(1R)-1-(4-Fluoro-3-methoxyphenyl)ethan-1-amine--hydrogen chloride (1/1)

C9H13ClFNO

结构：O=C1CC[C@@H](c2ccc(CCS(=O)(=O)N3CCOCC3)cc2)C1
HCID68751067

未命名化合物

PRODUCTS

生成物

1
结构：COc1cc([C@@H](C)NC2CC[C@@H](c3ccc(CCS(=O)(=O)N4CCOCC4)cc3)C2)ccc1F
HCID68093342

未命名化合物

PROCEDURE

实验过程

General procedure B was followed using (3R)-3-{4-[2-(morpholine-4-sulfonyl)-ethyl]-phenyl}-cyclopentanone (preparation 49) as the ketone and (1R)-1-(4-fluoro-3-methoxyphenyl)ethylamine hydrochloride as the amine. 1H NMR (300 MHz, DMSO) δ 7.23-7.04 (m, 6H), 6.92-6.83 (m, 1H), 3.82 (s, 3H), 3.80-3.68 (m, 1H), 3.66-3.55 (m, 4H), 3.37-3.26 (m, 2H), 3.22-3.10 (m, 4H), 3.06-2.78 (m, 4H), 2.20-1.13 (m, 6H), 1.23 (d, J=6.6 Hz, 3H).