反应详情

Compound is prepared from 4′-fluoro-2′-methyl-biphenyl-3-carboxylic acid[4-(2-methylsulfanyl-pyrimidin-4-yloxy)-naphthalen-1-yl]-amide and N,N,2,2-tetramethyl-1,3-propanediamine according to conditions described in general procedure J. (23 mg). 1H NMR (400 MHz, CDCl3) δ 8.01-8.1(m, 4H), 7.88(dd, 1H, J=0.8 and 8 Hz), 7.5-7.65(m, 5H), 7.26-7.33(m, 2H), 6.98-7.08(m, 2H), 6.21(d, 1H, J=6 Hz), 2.3(s, 3H), 2.0-2.2(brm, 10H), 0.6-0.9(brs, 6H).