反应详情

The title compound was prepared using the procedure described in Example 190 substituting 2-(2-oxo-3,3-diphenylpyrrolidin-1-yl)acetic acid from Example 1C for 2-(3,3-bis(4-fluorophenyl)-2-oxopyrrolidin-1-yl)acetic acid and (Z)—N-hydroxy-4-methylbenzimidamide for (Z)—N-hydroxy-4-(trifluoromethyl)benzimidamide. 1H NMR (300 MHz, CDCl3) δ ppm 7.93-7.87 (m, 2H), 7.43-7.22 (m, 10H), 7.08 (s, 1H), 6.90-6.81 (m, 1H), 4.88 (s, 2H), 3.56 (t, J=6.5, 2H), 2.88 (t, J=6.5, 2H), 2.42 (s, 3H)); MS (DCI) m/z 410.1 (M+H)+.