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HRID1711254

反应详情

EQUATION

反应方程式

HRID 1711254 的结构方程式

REACTANTS

反应物

2
结构：CC(=O)c1ccc(Br)c([N+](=O)[O-])c1
HCID87737

1-(4-Bromo-3-nitrophenyl)ethan-1-one

C8H6BrNO3

结构：CC1(C)CC=C(B(O)O)CC1
HCID44119555

(4,4-Dimethylcyclohex-1-en-1-yl)boronic acid

C8H15BO2

PRODUCTS

生成物

1
结构：CC(=O)c1ccc(C2=CCC(C)(C)CC2)c([N+](=O)[O-])c1
HCID58754813

未命名化合物

收率 99.2%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCCCCC.CCOC(C)=O
溶剂HCID21226206

未命名化合物

PROCEDURE

实验过程

The title compound was prepared by the Suzuki coupling procedure of Example 11, step (e) using 1-(4-bromo-3-nitro-phenyl)-ethanone (347 mg, 1.42 mmol), and 4,4-dimethylcyclohexen-1-ylboronic acid (254 mg, 1.65 mmol). Silica gel chromatography (5-15% EtOAc/hexane) afforded the title compound (385 mg, 99%) as a faint green oil. Mass spectrum (APCI, m/z): Calcd. for C16H19NO3, 274.1 (M+H), found 274.0.

WORKUP

后处理

  1. customThe title compound was prepared by the Suzuki coupling procedure of Example 11, step (e)