Acetic Anhydride → HCID 14746274, compound
Reaction equation
[CH3:1][C:2]1[C:7]([OH:8])=[C:6]([CH3:9])[CH:5]=[C:4]([C:10]([CH3:12])=[O:11])[CH:3]=1.[C:13](OC(=O)C)(=[O:15])[CH3:14]>>[CH3:1][C:2]1[CH:3]=[C:4]([CH:10]([OH:11])[CH3:12])[CH:5]=[C:6]([CH3:9])[C:7]=1[O:8][C:13](=[O:15])[CH3:14]Participants
3
Procedure
In the process for the production of 3,5-dimethyl-4-acetoxystyrene monomer, one may begin with commercially available 2,6-dimethyl phenol and esterify it with acetic anhydride to produce 2,6-dimethyl phenyl acetate. Then, via a Friedel-Crafts catalysis or Fries rearrangement this is converted to 3,5-dimethyl-4-hydroxy acetophenone. The 3,5-dimethyl-4-hydroxy acetophenone is then esterified with acetic anhydride. The latter is then hydrogenated to form 1-(3,5-dimethyl-4-acetoxyphenyl)ethanol. This is then dehydrated with an acid to form 3,5-dimethyl-4-acetoxystyrene monomer, copolymerized with unsubstituted 4-acetoxystyrene, and hydrolyzed to produce poly (3,5,-dimethyl-4-hydroxystyrene-co-4-hydroxystyrene).
Sources & evidence
- ORD record
- ord-06ab9355f95440268ac6987f23e21da0
- Source dataset
- uspto-grants-1994_08
- Patent number
- US05342727
Reaction notes
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