反应详情

(S)-2-(methoxycarbonylamino)-1-((2S,4S)-2-(5-(7-(2-((2S,4S)-1-((R)-2-(t-butoxycarbonylamino)-2-phenylacetyl)-4-methylpyrrolidin-2-yl)-1H-imidazol-5-yl)-5,10-dihydrochromeno[5,4,3-cde]chromen-2-yl)-1H-imidazol-2-yl)-4-methylpyrrolidin-1-yl)-3-methylbutan-1-one, 86 mg, was treated with 0.76 mL 1.25N HCl in Ethanol at room temperature overnight, then at 50° C. for 1 hour. The mixture was concentrated under reduced pressure and further dried under high vacuum to give product (90 mg).

1. concentrationThe mixture was concentrated under reduced pressure
2. customfurther dried under high vacuum