反应详情

To a solution of N-(5-{1-[2-(tert-Butyl-dimethyl-silanyloxy)-1,1-dimethyl-ethyl]-7-fluoro-1H-pyrrolo[3,2-c]pyridine-3-carbonyl}-pyridin-3-yl)-2-(3-trifluoromethyl-phenyl)-acetamide (Preparation 3, 40 mg, 63 μmol) in THF (5 mL) 4M dioxane-HCl (0.5 mL) was added and stirred at room temperature for 2 hours. The reaction was evaporated in vacuo and triturated with pentane-ether to afford the title compound as a yellow solid in 86% yield, 28 mg.

1. customThe reaction was evaporated in vacuo
2. customtriturated with pentane-ether