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HRID1779174

反应详情

EQUATION

反应方程式

HRID 1779174 的结构方程式

REACTANTS

反应物

3
结构：CCCCOc1ccc(C[C@H](N)C(=O)OC)cc1
HCID68030835

未命名化合物

结构：CCCCCCCC(F)(F)CCCCCC/C=C/[C@H](C(=O)N[C@@H](Cc1ccc(OCCCC)cc1)C(=O)NC)[C@@](O)(CCOC)C(=O)O
HCID90060276

未命名化合物

结构：CCCCOc1ccc(C[C@H](N)C(=O)NC)cc1
HCID90060342

未命名化合物

PRODUCTS

生成物

1
结构：CCCCCCCC(F)(F)CCCCCC/C=C/[C@H](C(=O)N[C@@H](Cc1ccc(OCCCC)cc1)C(=O)NC)[C@@](O)(CCOC)C(=O)OC(C)(C)C
HCID131734850

未命名化合物

PROCEDURE

实验过程

tert-Butyl (E)-(2S,3S)-3-[(S)-2-(4-butoxy-phenyl)-1-methylcarbamoyl-ethylcarbamoyl]-12,12-difluoro-2-hydroxy-2-(2-methoxy-ethyl)-nonadec-4-enoate (PSI (LC/MS positive mode) ink 739 (M+H); Rt 2.72 min.) was synthesized using (S)-2-amino-3-(4-butoxy-phenyl)-N-methyl-propionamide and the conditions at 50° C. for 2.5 days instead of methyl (S)-2-amino-3-(4-butoxy-phenyl)-propionate and the conditions in Step B-7′. (E)-(2S,3S)-3-[(S)-2-(4-Butoxy-phenyl)-1-methylcarbamoyl-ethylcarbamoyl]-12,12-difluoro-2-hydroxy-2-(2-methoxy-ethyl)-nonadec-4-enoic acid (No. 5514404) was synthesized under conditions similar to those in the following Step B-8′.

WORKUP

后处理

  1. custom5514404) was synthesized under conditions similar to those in the following Step