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HRID1792177

反应详情

EQUATION

反应方程式

HRID 1792177 的结构方程式

REACTANTS

反应物

2
结构：C1CCOC1.CCCC[N+](CCCC)(CCCC)CCCC.[F-]
HCID11078149

未命名化合物

结构：CC[Si](CC)(CC)OC(C)(C)C#CCOCC1=CC[C@H]2C3=CC=C4C[C@@H](O[Si](C)(C)C(C)(C)C)C[C@H](O[Si](C)(C)C(C)(C)C)[C@]4(C)[C@H]3CC[C@]12C
HCID69630578

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(O)C#CCOCC1=CC[C@H]2C3=CC=C4C[C@@H](O)C[C@H](O)[C@]4(C)[C@H]3CC[C@]12C
HCID69629697

未命名化合物

收率 92%

PROCEDURE

实验过程

1α,3β-Bis(tert-butyldimethylsilyloxy)-17-(4-triethylsilyloxy-4-methyl-2-pentynyloxymethyl)androsta-5,7,16-triene (480 mg, 0.635 mmol) and 1M tetra-n-butylammonium fluoride tetrahydrofuran solution (6 ml) were subjected to reaction using a procedure similar to that of Example 5(2) (4 hours), worked up and purified by column chromatography (ethyl acetate:dichloromethane=4:1 followed by ethyl acetate) to give the titled compound (240 mg, 92%) as a pale yellow foam.

WORKUP

后处理

  1. customof Example 5(2) (4 hours)
  2. custompurified by column chromatography (ethyl acetate:dichloromethane=4:1 followed by ethyl acetate)