反应详情

3-Methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzoic acid methyl ester of Example 28, Step A (5.00 g, 18.1 mmol) and 3,4-dihydronaphthalen-1-yl trifluoromethanesulfonate (5.54 g, 19.9 mmol) were reacted in the manner of Example 1, Step F. Purification by flash column chromatography on silica gel, eluting with 10% ethyl acetate in hexane, afforded the title compound (4.90 g) as a light yellow oil.

1. customPurification by flash column chromatography on silica gel
2. washeluting with 10% ethyl acetate in hexane