反应详情

In a manner similar to that used in the preparation of the compound of example 2, but using 2-(5-methoxy-1H-indol-3-yl)acetic acid in step 7 (A) and 3,5-dichloro-4-aminobenzylamine (preparation A) in step 7 (B), the title compound was prepared. MS (ESI) (M+H)+=419.99 1H-NMR (500 MHz, CD3OD) δ 7.29 (d, J=8.85 Hz, 1 H), 7.25 (s, 1 H), 7.21 (s, 2 H), 7.03 (d, J=2.44 Hz, 1 H), 6.82 (dd, J=8.85, 2.44 Hz, 1 H), 4.33 (s, 2 H), 3.92 (s, 2 H), 3.82 (s, 3 H).