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HRID1819699

反应详情

EQUATION

反应方程式

HRID 1819699 的结构方程式

REACTANTS

反应物

3
结构：Cc1[nH]c2ccccc2c1CC(=O)O
HCID589107

2-Methylindole-3-acetic acid

C11H11NO2

结构：CC(=O)Nc1c(Cl)cc(CN)cc1Cl
HCID58962993

N-[4-(Aminomethyl)-2,6-dichlorophenyl]acetamide

C9H10Cl2N2O

结构：COc1ccc2[nH]cc(CC(=O)N=C(N)NCc3cc(Cl)c(NC(C)=O)c(Cl)c3)c2c1
HCID178488081

未命名化合物

PRODUCTS

生成物

1
结构：CC(=O)Nc1c(Cl)cc(CNC(N)=NC(=O)Cc2c(C)[nH]c3ccccc23)cc1Cl
HCID178474302

未命名化合物

PROCEDURE

实验过程

In a manner similar to that used in the preparation of the compound of example 2, but using 2-(2-methyl-1H-indol-3-yl)acetic acid in step 11 (A) and 4-acetamido-3,5-dichloro-benzylamine (preparation B) in step 11 (B), the title compound was prepared. MS (ESI) (M+H)+=446.08 1H-NMR (500 MHz, CD3OD) δ 7.36-7.50 (m, 3 H), 7.30 (d, J=7.93 Hz, 1 H), 7.00-7.10 (m, 2 H), 4.52 (s, 2 H), 3.92 (s, 2 H), 2.44 (s, 3 H), 2.19 (s, 3 H).