HRID1819710

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(C)(C)NC(=O)c1[nH]c2ccc(Br)cc2c1CC(=O)O

HCID57887237

未命名化合物

结构：CC(=O)Nc1c(Cl)cc(CNC(N)=NC(=O)Cc2c[nH]c3cc(Br)ccc23)cc1Cl

HCID178474305

未命名化合物

PRODUCTS

生成物

结构：CC(=O)Nc1c(Cl)cc(CNC(N)=NC(=O)Cc2c(C#N)[nH]c3ccc(Br)cc23)cc1Cl

HCID178474304

未命名化合物

PROCEDURE

实验过程

In a manner similar to that used in the preparation of the compound of example 1, but using 2-(5-bromo-2-(tert-butylcarbamoyl)-1H-indol-3-yl)acetic acid (preparation J) in step 25 (A), the title compound was prepared. 1H-NMR (500 MHz, CD3OD) δ ppm 2.19 (d, J=12.82 Hz, 3 H) 3.79 (s, 2 H) 4.31 (s, 2 H) 7.00 (s, 1 H) 7.26 (s, 1 H) 7.35 (d, J=8.24 Hz, 1 H) 7.85 (s, 1 H).