反应详情

The title compound was prepared according to the method used for the preparation of 2-(2-methoxypyrimidin-5-yl)-1,3-benzothiazole, now starting from 1,3-benzothiazol-5-amine (50 mg, 0.33 mmol) and 5-bromo-N-methylpyridin-2-amine (75 mg, 0.40 mmol). The crude material was purified on a preparative HPLC to give the title compound (12 mg) as a pale beige solid. 1H NMR δ ppm 8.62 (d, 1 H) 7.95 (dd, 1 H) 7.61 (d, 1 H) 7.19 (q, 1 H) 7.07 (d, 1 H) 6.69 (dd, 1 H) 6.56 (d, 1 H) 5.24 (s, 2 H) 2.85 (d, 3 H); MS m/z (M+H) 257.

1. customThe title compound was prepared
2. customThe crude material was purified on a preparative HPLC