反应详情

2.40 g (5.72 mmol) of 2-but-1-enyl-5-(4′-ethyl-2,3-difluorobiphenyl-4-yl)-selenophene are hydrogenated in 25 ml of ethyl acetate, in the presence of Pd/C (5% of Pd) at atmospheric pressure and RT. The reaction soln. is filtered and concentrated to dryness, and the crude product is purified by column chromatography (SiO2, n-heptane:toluene=9:1). The further purification is carried out by recrystallisation from ethanol and n-heptane. 2-Butyl-5-(4′-ethyl-2,3-difluorobiphenyl-4-yl)selenophene is obtained as a colourless solid (m.p. 73° C.).

1. filtrationis filtered
2. concentrationconcentrated to dryness
3. customthe crude product is purified by column chromatography (SiO2, n-heptane:toluene=9:1)
4. customThe further purification
5. customis carried out by recrystallisation from ethanol and n-heptane