反应详情

The procedure of Preparation Example 2 was repeated, except that 55 mg of N-(4′-methoxybiphenyl-4-yl)methanesulfonamide was used in place of 4′-methoxy-2-biphenylacetonitrile, and 1,2-dichloroethane was used in place of methylene chloride. The resulting crude product was purified by TLC (using a 6:1 mixture of chloroform and acetone as the developing solvent) to obtain 24 mg of N-(4′-hydroxybiphenyl-4-yl)-methanesulfonamide.

1. customThe procedure of Preparation Example 2
2. customThe resulting crude product was purified by TLC (
3. additiona 6:1 mixture of chloroform and acetone as the developing solvent)