HRID1888267

反应详情

EQUATION

反应方程式

HRID 1888267 的结构方程式

AUXILIARIES

试剂、催化剂与溶剂

1

PROCEDURE

实验过程

The title compound was prepared according to the general procedure of Example 38b. Thus, 3-{1-[(3-Chloropropyl)sulfonyl]-4-piperidinyl}-5-(3-fluorophenyl)-1H-indazole-7-carboxamide (Example 38a) (0.222 mmol) in DMF (4 mL) was reacted with K2CO3 (61 mg, 0.444 mmol) and 4-hydroxy piperidine (112 mg, 1.11 mmol) to afford the title compound (32.07 mg, 27% for 2 steps).

WORKUP

后处理

  1. customThe title compound was prepared