HRID1888698

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID12618374

Cyclobutanamine--hydrogen chloride (1/1)

C4H10ClN

$结构：CCCCc1cn(C(C)(C)C)s/c1=N\C(=O)[C@]1(C)CC[C@H](C(=O)O)C1(C)C$

HCID178441278

未命名化合物

PRODUCTS

生成物

$结构：CCCCc1cn(C(C)(C)C)s/c1=N\C(=O)[C@]1(C)CC[C@H](C(=O)NC2CCC2)C1(C)C$

HCID178441269

未命名化合物

PROCEDURE

实验过程

The product from Example 173 and cyclobutylamine hydrochloride (Aldrich) were processed using the method described in Example 178 to afford the title compound. 1H NMR (DMSO-d6) δ 0.00 (s, 3H), 0.44 (t, J=7.3 Hz, 3H), 0.74 (s, 3H), 0.77 (s, 3H), 0.80-0.98 (m, 3H), 1.11 (s, 9H), 1.11-1.21 (m, 5H), 1.32-1.57 (m, 3H), 1.62-1.72 (m, 2H), 2.13-2.21 (m, 3H), 2.26-2.36 (m, 1H), 3.67-3.80 (m, 1H), 7.32 (d, J=7.7 Hz, 1H), 8.04 (s, 1H). (ESI+) m/z 448 (M+H)+. Anal. calcd. for C25H41N3O2S: C, 67.07; H, 9.23; N, 9.39. Found: C, 66.48; H, 9.40; N, 9.24.