反应详情

From the mixture of 5-(benzyloxy)-3-p-tolyl-3H-imidazo[4,5-b]pyridine and 5-(benzyloxy)-1-p-tolyl-1H-imidazo[4,5-b]pyridine, the benzyl group was removed as described in Example 1.11, Step B. Purification by preparative HPLC gave the title compound as a white solid. 1H NMR (400 MHz, methanol-d4) δ ppm 2.41 (s, 3H), 6.70 (d, J=8.8 Hz, 1H), 7.36 (d, J=8.3 Hz, 2H), 7.67 (d, J=8.3 Hz, 2H), 7.95 (d, J=8.6 Hz, 1H), 8.43 (s, 1H).

1. customthe benzyl group was removed
2. customPurification by preparative HPLC