反应详情

Using the procedure of Example 2, step 2.i, but starting from 7-methoxy-2(1H)-quinolinone (prepared according to WO 2006/134378; 500 mg) and 3-[[(methylsulfonyl)oxy]methyl]-1-pyrrolidinecarboxylic acid tert-butyl ester (797 mg; prepared according to J. Med. Chem. (1999), 42, 677-690), the second eluting compound was isolated as a colourless oil (240 mg; 23% yield).

1. customthe second eluting compound was isolated as a colourless oil (240 mg; 23% yield)